Description
What is Testosterone Enanthate?
Testosterone enanthate is a 17-beta-hydroxy ester of testosterone, often sold under brand names like Delatestryl (intramuscular) or Xyosted (subcutaneous). As a long-acting prodrug, it is inactive until it enters the body, where esterase enzymes break its chemical bond to release bioidentical testosterone into the bloodstream.
Testosterone enanthate Key Medical Uses
- Male Hypogonadism: Primarily used to treat primary and secondary hypogonadism (low T), helping to restore libido, energy, and muscle mass.
- Delayed Puberty: Prescribed to adolescent males to stimulate the development of secondary sexual characteristics.
- Breast Cancer Palliation: Used as a secondary treatment for inoperable, metastatic mammary cancer in women.
- Gender-Affirming Therapy: Often utilized in transgender men to promote masculinization.
Standard Administration:
The administration and frequency vary based on the patient’s condition and response to therapy, as determined by a healthcare professional.
- Intramuscular (IM) Injection: This is a common method of administration. The frequency can range from every two to four weeks. Some clinicians may recommend more frequent injections, such as weekly, to help maintain more stable hormone levels.
- Subcutaneous (SQ) Injection: For specific formulations, this method involves self-administration, often in the abdominal region. The typical frequency is once weekly.
Safety, Side Effects, and Risks
While effective, this medication carries significant risks and potential side effects:
- Common Side Effects: Acne, injection site pain, increased red blood cell count (erythrocytosis), and mood changes.
- Serious Risks: Increased risk of blood clots, heart attack, stroke, and liver damage.
- Contraindications: Must not be used by individuals with male breast or prostate cancer or those who are pregnant.
Testosterone Enanthate
In the United States, it is a Schedule III Controlled Substance due to the potential for misuse, dependency, and addiction, particularly when used off-label for athletic performance.
For further guidance, consult the Full Prescribing Information (FDA) or the Mayo Clinic Drug Reference.
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Disclaimer: This information is for general knowledge and should not be taken as medical advice. Consult with a healthcare professional before starting any new supplement regimen
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