Description
Oxandrolone (Anavar)
Oxandrolone (Anavar), commonly known by the brand name Anavar, is a synthetic anabolic-androgenic steroid (AAS) derived from dihydrotestosterone (DHT). It was first introduced in the 1960s to promote weight gain, reverse muscle loss due to surgery, chronic infections, or severe trauma, and treat osteoporosis-related bone pain. It is widely considered a “mild” steroid due to its high anabolic (muscle-building) to low androgenic (masculinizing) ratio, but it still carries significant health risks.
Key Aspects of Oxandrolone (Anavar):
- Medical Uses: FDA-approved to treat weight loss after severe trauma/surgery, counteract catabolic effects of long-term corticosteroid use, and aid recovery in burn patients.
- Bodybuilding/Athletic Use: Often used to “cut” fat and preserve lean muscle mass due to its low water retention.
- Mechanism of Action: Mimics testosterone to stimulate protein synthesis, improve nitrogen retention, and build muscle.
- Administration: Typically taken orally, with a half-life of 9–10 hours, necessitating daily, often divided, doses.
Oxandrolone (Anavar) Side Effects and Risks:
Despite being considered “mild,” Oxandrolone can cause serious side effects, particularly with misuse:
- Liver Toxicity: As a 17-alpha-alkylated oral steroid, it can cause elevated liver enzymes, jaundice, and in rare cases, liver tumors or peliosis hepatis.
- Cardiovascular Issues: It lowers “good” (HDL) cholesterol and increases “bad” (LDL) cholesterol, raising the risk of heart disease.
- Hormonal Suppression: It can suppress natural testosterone production in men, leading to low libido, erectile dysfunction, and testicular atrophy.
- Virilization (Women): Women may experience irreversible changes, such as voice deepening, facial hair growth, and menstrual irregularities.
- Pediatric Issues: It can stunt growth in children by causing premature bone maturation.
Oxandrolone (Anavar) Legal Status and Availability:
In the United States, Oxandrolone is a Schedule III controlled substance. As of June 2023, the FDA formally withdrew approval for all oral doses of oxandrolone in the US, citing insufficient evidence of efficacy and serious safety risks. It is generally illegal to possess or use without a prescription, and it is no longer available in many countries, including those in Europe.
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